| Tdark | Tubulin gamma-2 chain |
Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).
Comments
| Disease | Target Count | P-value |
|---|---|---|
| ependymoma | 4679 | 6.2e-12 |
| atypical teratoid / rhabdoid tumor | 5112 | 1.0e-08 |
| glioblastoma | 5792 | 2.3e-08 |
| Astrocytoma, Pilocytic | 3081 | 1.0e-06 |
| medulloblastoma, large-cell | 6241 | 1.3e-06 |
| Pick disease | 1894 | 5.6e-06 |
| adult high grade glioma | 3801 | 6.5e-05 |
| group 3 medulloblastoma | 4104 | 7.8e-05 |
| primitive neuroectodermal tumor | 3035 | 1.5e-04 |
| interstitial cystitis | 2312 | 1.0e-03 |
| osteosarcoma | 7950 | 2.4e-03 |
| subependymal giant cell astrocytoma | 2287 | 1.4e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Pilocytic astrocytoma | 56 | 3.369 | 1.7 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -1.800 | 6.5e-05 |
| Astrocytoma, Pilocytic | -1.300 | 1.0e-06 |
| atypical teratoid / rhabdoid tumor | -2.000 | 1.0e-08 |
| ependymoma | -1.800 | 6.2e-12 |
| glioblastoma | -1.800 | 2.3e-08 |
| group 3 medulloblastoma | -2.000 | 7.8e-05 |
| interstitial cystitis | -1.200 | 1.0e-03 |
| medulloblastoma, large-cell | -3.200 | 1.3e-06 |
| osteosarcoma | -1.173 | 2.4e-03 |
| Pick disease | -1.500 | 5.6e-06 |
| primitive neuroectodermal tumor | -1.400 | 1.5e-04 |
| subependymal giant cell astrocytoma | -1.429 | 1.4e-02 |
MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLE 1 - 70 PRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHS 71 - 140 IAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPYQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTAL 141 - 210 NRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQ 211 - 280 SVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIP 281 - 350 WGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFESSCQQFDKLRKRDAFLEQFRKEDMFKDNFDE 351 - 420 MDRSREVVQELIDEYHAATQPDYISWGTQEQ 421 - 451 //
