Tchem SNRK SNF-related serine/threonine-protein kinase

Protein Summary

Description

May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis. SNRK is a member of the sucrose nonfermenting (SNF)-related kinase family of serine/threonine kinases (Kertesz et al., 2002 [PubMed 12234663]).[supplied by OMIM, Apr 2009]

Uniprot Accession IDs

• Q9NRH2
• B2RAV6
• Q14706
• Q68D15
• Q6IQ46
• Q9NXI7

Gene Name

• SNRK

Ensembl ID

• ENST00000296088
• ENSP00000296088
• ENSG00000163788
• ENST00000429705
• ENSP00000411375
• ENST00000454177
• ENSP00000401246

Symbol

• KIAA0096
• SNFRK
• HSNFRK

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.97
disease perturbation	0.96
molecular function	0.94
protein domain	0.85
virus perturbation	0.85

Protein Classes

PANTHER Classes

Protein / Transferase / Kinase / Protein Kinase / Non-receptor Serine/threonine Protein Kinase / Snf-related Serine/threonine-protein Kinase

DTO Classes

Protein / Kinase / Protein Kinase / Camk Group / Camkl Family / Snrk Subfamily / Snf-related Serine/threonine-protein Kinase

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 180.3   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 142   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 180.3   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 142   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0