Tbio PXMP2 Peroxisomal membrane protein 2

Protein Summary

Description

Seems to be involved in pore-forming activity and may contribute to the unspecific permeability of the peroxisomal membrane.

Uniprot Accession IDs

• Q9NR77

Gene Name

• PXMP2

Ensembl ID

• ENST00000317479
• ENSP00000321271
• ENSG00000176894

Symbol

• PMP22
• PMP22

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	0.93
cellular component	0.79
virus perturbation	0.79
cell type or tissue	0.75
histone modification site profile	0.74

Protein Classes

PANTHER Classes

Protein / Transmembrane Receptor Regulatory/adaptor Protein / Peroxisomal Membrane Protein 2

DTO Classes

Protein / Receptor / Peroxisomal Membrane Protein 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.11   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 111   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.11   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 111   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0