MAN1C1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC
Protein Summary
Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc.
- ENST00000374332
- ENSP00000363452
- ENSG00000117643
- MAN1A3
- MAN1C
- HMIC
- MAN1C
- MAN1A3
- pp6318
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
PubMedID | 0.79 | ||
transcription factor binding site profile | 0.77 | ||
transcription factor | 0.72 | ||
virus perturbation | 0.72 | ||
cellular component | 0.68 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 16.34 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 52 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 16.34 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 52 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0