Property Summary

NCBI Gene PubMed Count 7
PubMed Score 2.18
PubTator Score 357.37

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (1)

Disease Target Count P-value
lung carcinoma 2844 5.22545170838268E-27
tuberculosis 1563 8.24061458909694E-7
group 4 medulloblastoma 1875 4.33302987243083E-6
ovarian cancer 8492 3.98220088829486E-4
diabetes mellitus 1663 0.00133526895939173
medulloblastoma, large-cell 6234 0.00296086944688082
non primary Sjogren syndrome sicca 840 0.0172946890926187
oligodendroglioma 2849 0.0177518265474098
astrocytic glioma 2241 0.0347067962231327

Expression

  Differential Expression (9)

Disease log2 FC p
astrocytic glioma -1.300 0.035
oligodendroglioma -1.700 0.018
group 4 medulloblastoma -2.200 0.000
medulloblastoma, large-cell -1.100 0.003
tuberculosis 1.200 0.000
diabetes mellitus -1.100 0.001
non primary Sjogren syndrome sicca 1.200 0.017
lung carcinoma -1.500 0.000
ovarian cancer 1.300 0.000

Synonym

Accession Q9NR33 Q53TR2
Symbols p12
YHHQ1

Gene

  Ortholog (9)

 GO Process (1)

Gene RIF (1)

PMID Text
22190034 HIV-1 PR is identified to have a physical interaction with polymerase (DNA directed), epsilon 4 (POLE4) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses

AA Sequence

MAAAAAAGSGTPREEEGPAGEAAASQPQAPTSVPGARLSRLPLARVKALVKADPDVTLAGQEAIFILARA      1 - 70
AELFVETIAKDAYCCAQQGKRKTLQRRDLDNAIEAVDEFAFLEGTLD                            71 - 117
//

Text Mined References (13)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
22814378 2012 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
22190034 2011 Global landscape of HIV-human protein complexes.
21269460 2011 Initial characterization of the human central proteome.
20068231 2010 Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
19413330 2009 Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
18838386 2008 Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.
17525332 2007 ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
15815621 2005 Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
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