| Tdark | Intraflagellar transport protein 46 homolog |
Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity).
Comments
| Disease | Target Count | P-value |
|---|---|---|
| lung cancer | 4740 | 3.9e-03 |
| ependymoma | 4679 | 3.1e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Joubert syndrome | 66 | 4.347 | 2.2 |
| Meckel syndrome | 46 | 3.733 | 1.9 |
| Primary ciliary dyskinesia | 76 | 3.475 | 1.7 |
| Hydrocephalus | 152 | 3.422 | 1.7 |
| Nephronophthisis | 80 | 3.167 | 1.6 |
MADNSSDECEEENNKEKKKTSQLTPQRGFSENEDDDDDDDDSSETDSDSDDDDEEHGAPLEGAYDPADYE 1 - 70 HLPVSAEIKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKPDNLGLLVLDEPSTK 71 - 140 QSDPTVLSLWLTENSKQHNITQHMKVKSLEDAEKNPKAIDTWIESISELHRSKPPATVHYTRPMPDIDTL 141 - 210 MQEWSPEFEELLGKVSLPTAEIDCSLAEYIDMICAILDIPVYKSRIQSLHLLFSLYSEFKNSQHFKALAE 211 - 280 GKKAFTPSSNSTSQAGDMETLTFS 281 - 304 //
