Property Summary

NCBI Gene PubMed Count 11
PubMed Score 3.13
PubTator Score 3.92

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (1)

Disease Target Count P-value
lung adenocarcinoma 2714 1.04286352322356E-10
ulcerative colitis 2087 1.33592252529784E-6
Breast cancer 3099 4.00099857287795E-6
atypical teratoid/rhabdoid tumor 1095 1.97105284409542E-4
intraductal papillary-mucinous carcinoma (IPMC) 2988 9.90137105965734E-4
interstitial cystitis 2299 0.00190579406775814
osteosarcoma 7933 0.00547242358420467
intraductal papillary-mucinous neoplasm (IPMN) 3289 0.0147106383940473
ependymoma 2514 0.0253526249798225

Expression

  Differential Expression (9)

Synonym

Accession Q9HCJ3 Q6P141 Q9NPV7
Symbols

Gene

PDB

1WG1  

  Ortholog (10)

Species Source
Chimp OMA EggNOG
Macaque OMA EggNOG Inparanoid
Mouse OMA Inparanoid
Rat OMA Inparanoid
Dog OMA Inparanoid
Cow OMA EggNOG Inparanoid
Opossum OMA EggNOG Inparanoid
Platypus OMA Inparanoid
Anole lizard OMA Inparanoid
Xenopus OMA EggNOG Inparanoid

Gene RIF (4)

PMID Text
25637521 Deregulation of LMNB1 expression induces modified splicing of several genes, likely driven by raver-2 overexpression, and suggest that an alteration of mRNA processing could be a pathogenic mechanism in adult-onset autosomal dominant leukodystrophy.
22561236 genetic polymorphism is ssociated with increased susceptibility for ulcerative colitis
22146317 Together, our results suggest that regulation of human Raver2 expression involves TATA-less transcriptional activity.
20237496 Observational study of gene-disease association. (HuGE Navigator)

AA Sequence

MAAAAGDGGGEGGAGLGSAAGLGPGPGLRGQGPSAEAHEGAPDPMPAALHPEEVAARLQRMQRELSNRRK      1 - 70
ILVKNLPQDSNCQEVHDLLKDYDLKYCYVDRNKRTAFVTLLNGEQAQNAIQMFHQYSFRGKDLIVQLQPT     71 - 140
DALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTGHSKGYGFVEYMKKDFAAKARLELLGRQLGA    141 - 210
SALFAQWMDVNLLASELIHSKCLCIDKLPSDYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYS    211 - 280
TAEQAEEVQQAADGMTIKGSKVQVSFCAPGAPGRSTLAALIAAQRVMHSNQKGLLPEPNPVQIMKSLNNP    281 - 350
AMLQVLLQPQLCGRAVKPAVLGTPHSLPHLMNPSISPAFLHLNKAHQSSVMGNTSNLFLQNLSHIPLAQQ    351 - 420
QLMKFENIHTNNKPGLLGEPPAVVLQTALGIGSVLPLKKELGHHHGEAHKTSSLIPTQTTITAGMGMLPF    421 - 490
FPNQHIAGQAGPGHSNTQEKQPATVGMAEGNFSGSQPYLQSFPNLAAGSLLVGHHKQQQSQPKGTEISSG    491 - 560
AASKNQTSLLGEPPKEIRLSKNPYLNLASVLPSVCLSSPASKTTLHKTGIASSILDAISQGSESQHALEK    561 - 630
CIAYSPPFGDYAQVSSLRNEKRGSSYLISAPEGGSVECVDQHSQGTGAYYMETYLKKKRVY             631 - 691
//

Text Mined References (15)

PMID Year Title
25637521 2015 Messenger RNA processing is altered in autosomal dominant leukodystrophy.
22814378 2012 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
22681889 2012 The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
22658674 2012 Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
22561236 2012 Association of the RAVER2 gene with increased susceptibility for ulcerative colitis.
22146317 2012 Transcriptional regulation of the human Raver2 ribonucleoprotein gene.
20237496 2010 New genetic associations detected in a host response study to hepatitis B vaccine.
19413330 2009 Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
18669648 2008 A quantitative atlas of mitotic phosphorylation.
17974005 2007 The full-ORF clone resource of the German cDNA Consortium.
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