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Tbio
LRRC4C
Leucine-rich repeat-containing protein 4C

Protein Summary
Description
May promote neurite outgrowth of developing thalamic neurons. NGL1 is a specific binding partner for netrin G1 (NTNG1; MIM 608818), which is a member of the netrin family of axon guidance molecules (Lin et al., 2003 [PubMed 14595443]).[supplied by OMIM, Mar 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000278198
  • ENSP00000278198
  • ENSG00000148948
  • ENST00000527150
  • ENSP00000436976
  • ENST00000528697
  • ENSP00000437132
  • ENST00000530763
  • ENSP00000434761
  • ENST00000619527
  • ENSP00000480903

Symbol
  • KIAA1580
  • NGL1
  • NGL1
  • NGL-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
1
trait
0.86
transcription factor
0.62
cell line
0.59
disease
0.59


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.16   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 187   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.16   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 187   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0