Tbio ZNF160 Zinc finger protein 160

Protein Summary

Description

May be involved in transcriptional regulation. The protein encoded by this gene is a Kruppel-related zinc finger protein which is characterized by the presence of an N-terminal repressor domain, the Kruppel-associated box (KRAB). The KRAB domain is a potent repressor of transcription; thus this protein may function in transcription regulation. Multiple transcript variants have been found for this gene. [provided by RefSeq, Apr 2016]

Uniprot Accession IDs

• Q9HCG1
• Q14589
• Q504Q8
• Q96JC5
• Q9BVY9
• Q9H7N6

Gene Name

• ZNF160

Ensembl ID

• ENST00000355147
• ENSP00000347273
• ENSG00000170949
• ENST00000418871
• ENSP00000409597
• ENST00000429604
• ENSP00000406201
• ENST00000599056
• ENSP00000470961

Symbol

• KIAA1611
• F11
• HZF5
• KR18
• HKr18

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.72
cell type or tissue	0.7
tissue sample	0.62
protein domain	0.58
tissue	0.58

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.74   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 76   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.74   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0