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Tbio Ribosome production factor 2 homolog

Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus.

 Comments

Property Summary

NCBI Gene PubMed Count 13
PubMed Score 7.55
PubTator Score 4.14

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count Z-score Confidence
Sleeping sickness 37 3.626 1.8

Expression

  Differential Expression (3)

Disease log2 FC p
intraductal papillary-mucinous neoplasm ... -1.200 7.4e-03
ovarian cancer 1.400 3.8e-04
subependymal giant cell astrocytoma 1.442 2.0e-02

Synonym

Accession Q9H7B2 Q5VXN1 Q8N4A1
Symbols BXDC1
bA397G5.4

Gene

RPF2

PANTHER Protein Class (2)

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

 UniProt Keyword (5)

 GO Function (3)

 GO Component (2)

 GO Process (5)

 Compartment GO Term (26)

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 HCA RNA Cell Line (56)

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Gene RIF (1)

AA Sequence 

MDTLDRVVKPKTKRAKRFLEKREPKLNENIKNAMLIKGGNANATVTKVLKDVYALKKPYGVLYKKKNITR      1 - 70
PFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGIENFVSLKDIKNSKCPEGTK     71 - 140
PMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLAGLEYVLHFTALNGKIYFRSYKLLLKKSGCRTP    141 - 210
RIELEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRK    211 - 280
MKGLKKRPAERITEDHEKKSKRIKKN                                                281 - 306
//

Text Mined References (15)

PMID Year Title