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  5. Ribosome production factor 2 homolog

Tbio Ribosome production factor 2 homolog


 Comments

Property Summary

NCBI Gene PubMed Count 12
Grant Count 1
R01 Count 1
Funding $95,409
PubMed Score 7.48
PubTator Score 4.14

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (3)

Disease Z-score Confidence
intraductal papillary-mucinous neoplasm ... 3,289 
ovarian cancer 8,484
subependymal giant cell astrocytoma 2,287

Expression

  Differential Expression (3)

Disease log2 FC p
intraductal papillary-mucinous neoplasm ... -1.200 0.007
subependymal giant cell astrocytoma 1.442 0.020
ovarian cancer 1.400 0.000

Synonym

Accession Q9H7B2 Q5VXN1 Q8N4A1
Symbols BXDC1
bA397G5.4

Gene

RPF2

PANTHER Protein Class (2)

 Grant Application (1)

 GO Function (2)

 GO Component (2)

 GO Process (2)

 Compartment GO Term (25)

See all...

 UniProt Keyword (4)

Gene RIF (1)

PMID Text
19170763 BXDC1 and EBNA1BP2 function in a dynamic scaffold for ribosome biogenesis.

AA Sequence 

MDTLDRVVKPKTKRAKRFLEKREPKLNENIKNAMLIKGGNANATVTKVLKDVYALKKPYGVLYKKKNITR      1 - 70
PFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGIENFVSLKDIKNSKCPEGTK     71 - 140
PMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLAGLEYVLHFTALNGKIYFRSYKLLLKKSGCRTP    141 - 210
RIELEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGTTYGRIHMQKQDLSKLQTRK    211 - 280
MKGLKKRPAERITEDHEKKSKRIKKN                                                281 - 306
//

Text Mined References (14)

PMID Year Title
22681889 2012 The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
22658674 2012 Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
21269460 2011 Initial characterization of the human central proteome.
19170763 2009 Proteomic and targeted analytical identification of BXDC1 and EBNA1BP2 as dynamic scaffold proteins in the nucleolus.
18029348 2008 Toward a confocal subcellular atlas of the human proteome.
17353931 2007 Large-scale mapping of human protein-protein interactions by mass spectrometry.
17207965 2007 hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
15635413 2005 Nucleolar proteome dynamics.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
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