Tbio TMEM38A Trimeric intracellular cation channel type A

Protein Summary

Description

Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

Uniprot Accession IDs

• Q9H6F2
• A8K9P9
• TRIC-A

Gene Name

• TMEM38A

Ensembl ID

• ENST00000187762
• ENSP00000187762
• ENSG00000072954

Symbol

• TRICA
• TRIC-A

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cellular component	0.77
transcription factor binding site profile	0.65
transcription factor	0.62
molecular function	0.6
tissue	0.56

Protein Classes

DTO Classes

Protein / Ion Channel / Tmem38 Family / Trimeric Intracellular Cation Channel Type A

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.78   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 121   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.78   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 121   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0