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Tbio
EPHX3
Epoxide hydrolase 3

Protein Summary
Description
Catalyzes the hydrolysis of epoxide-containing fatty acids. Active in vitro against epoxyeicosatrienoic acids (EETs) including 8,9-EET, 9,10-EET, 11,12-EET and 14,15-EET and leukotoxin.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000221730
  • ENSP00000221730
  • ENSG00000105131
  • ENST00000435261
  • ENSP00000410323
  • ENST00000602233
  • ENSP00000469345

Symbol
  • ABHD9
  • EH3
  • ABHD9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.67
PubMedID
0.6
tissue
0.52
transcription factor
0.52
chemical
0.44


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 58.36   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 116   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 58.36   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 116   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0