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Tbio
OSGEPL1
Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial

Protein Summary
Description
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000264151
  • ENSP00000264151
  • ENSG00000128694
  • ENST00000519810
  • ENSP00000428859
  • ENST00000522700
  • ENSP00000429697

Symbol
  • GCP1
  • Qri7
  • OSGEPL
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.98
histone modification site profile
0.91
virus perturbation
0.79
kinase perturbation
0.71
transcription factor binding site profile
0.71


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.5   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 65   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.5   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 65   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0