| Tbio | Golgi phosphoprotein 3-like |
Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane.
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in Golgi trafficking. [provided by RefSeq, Jul 2008]
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in Golgi trafficking. [provided by RefSeq, Jul 2008]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| ovarian cancer | 8520 | 4.2e-07 |
| hepatocellular carcinoma | 547 | 6.2e-06 |
| intraductal papillary-mucinous adenoma (IPMA) | 2955 | 2.7e-04 |
| psoriasis | 6694 | 8.0e-04 |
| gastric cancer | 459 | 8.8e-04 |
| pancreatic cancer | 2398 | 4.4e-03 |
| pancreatic carcinoma | 562 | 4.4e-03 |
| Waldenstrons macroglobulinemia | 765 | 4.5e-03 |
| tuberculosis and treatment for 3 months | 179 | 6.4e-03 |
| astrocytoma | 1146 | 1.9e-02 |
| spina bifida | 1074 | 3.6e-02 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 3.7e-02 |
| acute myeloid leukemia | 783 | 3.9e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Cervical squamous cell carcinoma | 10 | 3.015 | 1.5 |
| Disease | log2 FC | p |
|---|---|---|
| acute myeloid leukemia | -1.300 | 3.9e-02 |
| astrocytoma | 1.100 | 1.9e-02 |
| gastric cancer | 1.100 | 8.8e-04 |
| hepatocellular carcinoma | 1.100 | 6.2e-06 |
| intraductal papillary-mucinous adenoma (... | 1.600 | 2.7e-04 |
| intraductal papillary-mucinous neoplasm ... | 1.200 | 3.7e-02 |
| ovarian cancer | -1.200 | 4.2e-07 |
| pancreatic cancer | 1.200 | 4.4e-03 |
| pancreatic carcinoma | 1.200 | 4.4e-03 |
| psoriasis | -1.200 | 8.0e-04 |
| spina bifida | -1.088 | 3.6e-02 |
| tuberculosis and treatment for 3 months | -1.100 | 6.4e-03 |
| Waldenstrons macroglobulinemia | 1.071 | 4.5e-03 |
MTTLTHRARRTEISKNSEKKMESEEDSNWEKSPDNEDSGDSKDIRLTLMEEVLLLGLKDKEGYTSFWNDC 1 - 70 ISSGLRGGILIELAMRGRIYLEPPTMRKKRLLDRKVLLKSDSPTGDVLLDETLKHIKATEPTETVQTWIE 71 - 140 LLTGETWNPFKLQYQLRNVRERIAKNLVEKGILTTEKQNFLLFDMTTHPVTNTTEKQRLVKKLQDSVLER 141 - 210 WVNDPQRMDKRTLALLVLAHSSDVLENVFSSLTDDKYDVAMNRAKDLVELDPEVEGTKPSATEMIWAVLA 211 - 280 AFNKS 281 - 285 //
