Property Summary

NCBI Gene PubMed Count 17
PubMed Score 7.21
PubTator Score 27.59

Knowledge Summary


No data available


  Disease (1)

Disease Target Count P-value
ovarian cancer 8491 1.1e-07
Rheumatoid Arthritis 1170 9.0e-03


  Differential Expression (2)

Disease log2 FC p
Rheumatoid Arthritis -1.300 9.0e-03
ovarian cancer -2.100 1.1e-07

Gene RIF (6)

26977013 CYPJ structurally resembles CYPA. It is sensitive to inhibition by CsA and plays a role in regulating cell growth, proliferation, and apoptosis.
26020957 Suppression of CYPJ could repress the growth of HCC, which makes CYPJ a potential target for the development of new strategies to treat this malignancy.
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
18474220 Human peptidyl-prolyl isomerase-like 3 (Ppil3) is one of the Apoptin-associated proteins.
16510998 Human cyclophilin J, a new member of the cyclophilin family, has been expressed and crystallized.
15989758 The novel full-length gene of human PPIL3 may be correlated with the formation of human glioma.

AA Sequence

YRPLNDVHIKDITIHANPFAQ                                                     141 - 161

Text Mined References (21)

PMID Year Title
26977013 2016 Biochemical Features of Recombinant Human Cyclophilin J.
26871637 2016 Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
26020957 2015 Cyclophilin J is a novel peptidyl-prolyl isomerase and target for repressing the growth of hepatocellular carcinoma.
25416956 2014 A proteome-scale map of the human interactome network.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
22365833 2012 Dynamic protein-protein interaction wiring of the human spliceosome.
22223895 2012 Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-?-acetylation features.
21269460 2011 Initial characterization of the human central proteome.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
19413330 2009 Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
18474220 2008 Interaction with Ppil3 leads to the cytoplasmic localization of Apoptin in tumor cells.
16510998 2005 Crystallization and preliminary X-ray crystallographic studies of human cyclophilin J.
16189514 2005 Towards a proteome-scale map of the human protein-protein interaction network.
15989758 2005 cDNA microarray in isolation of novel differentially expressed genes related to human glioma and clone of a novel full-length gene.
15815621 2005 Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
15735342 2005 Structure of recombinant human cyclophilin J, a novel member of the cyclophilin family.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11991638 2002 Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.
11435694 2001 Molecular cloning and characterization of a novel peptidylprolyl isomerase (cyclophilin)-like gene (PPIL3) from human fetal brain.