You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
SLC6A16
Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5

Protein Summary
Description
SLC6A16 shows structural characteristics of an Na(+)- and Cl(-)-dependent neurotransmitter transporter, including 12 transmembrane (TM) domains, intracellular N and C termini, and large extracellular loops containing multiple N-glycosylation sites.[supplied by OMIM, Mar 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000335875
  • ENSP00000338627
  • ENSG00000063127
  • ENST00000454748
  • ENSP00000404022

Symbol
  • NTT5
  • NT5
  • NTT5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.63
tissue sample
0.54
cell line
0.45
metabolite
0.45
microRNA
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.29   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 72   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.29   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 72   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0