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Tbio Transmembrane protease serine 13

This gene encodes a member of the type II transmembrane serine protease family. Transmembrane serine proteases are regulated by protease inhibitors and known to function in development, homeostasis, infection, and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

 Comments

Property Summary

NCBI Gene PubMed Count 10
PubMed Score 56.80
PubTator Score 34.91

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count P-value
ovarian cancer 8520 2.1e-06
medulloblastoma, large-cell 6241 1.2e-04
Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 0.7

Expression

  Differential Expression (2)

Disease log2 FC p
medulloblastoma, large-cell 1.100 1.2e-04
ovarian cancer -1.100 2.1e-06

Synonym

Accession Q9BYE2 B4DTM9 E9PIJ5 F8WAJ3 Q86YM4 Q96JY8 Q9BYE1
Symbols MSP
MSPL
MSPS
TMPRSS11

Gene

TMPRSS13

PANTHER Protein Class (3)

  Ortholog (8)

Species Source Disease
OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid EggNOG

 UniProt Keyword (14)

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 GO Function (2)

 GO Component (2)

 Compartment GO Term (5)

 MGI Phenotype (3)

 GWAS Trait (2)

 HCA RNA Cell Line (55)

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Pathway (1)

Gene RIF (5)

AA Sequence 

MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRAS      1 - 70
PGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRATPVGAVPIRSSPARSA     71 - 140
PATRATRESPGTSLPKFTWREGQKQLPLIGCVLLLIALVVSLIILFQFWQGHTGIRYKEQRESCPKHAVR    141 - 210
CDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHR    211 - 280
DFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHI    281 - 350
CGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRL    351 - 420
SKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYL    421 - 490
TPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMEV    491 - 560
RSLQQDTAPSRLGTSSGGDPGGAPRV                                                561 - 586
//

Text Mined References (10)

PMID Year Title