Tchem EBPL Emopamil-binding protein-like

Protein Summary

Description

Does not possess sterol isomerase activity and does not bind sigma ligands.

Uniprot Accession IDs

• Q9BY08
• A6NJ59
• Q569H7
• Q5JVN2
• Q5JVN3
• Q5JVN4
• Q5JVN5
• Q5JVN6

Gene Name

• EBPL

Ensembl ID

• ENST00000242827
• ENSP00000242827
• ENSG00000123179
• ENST00000378268
• ENSP00000367516
• ENST00000378270
• ENSP00000367519
• ENST00000378272
• ENSP00000367521

Symbol

• EBRP
• ERP
• EBRP

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.94
kinase perturbation	0.88
histone modification site profile	0.83
cell type or tissue	0.68
transcription factor perturbation	0.61

Protein Classes

PANTHER Classes

Protein / Isomerase / Emopamil-binding Protein-like

DTO Classes

Protein / Enzyme / Isomerase / Emopamil-binding Protein-like

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.2   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 64   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.2   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 64   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drugs: 2