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Tbio
C1QTNF4
Complement C1q tumor necrosis factor-related protein 4

Protein Summary
Description
May be involved in the regulation of the inflammatory network. Its role as pro- or anti-inflammatory seems to be context dependent (PubMed:21658842, PubMed:27086950). Seems to have some role in regulating food intake and energy balance when administered in the brain. This effect is sustained over a two-day period, and it is accompanied by decreased expression of orexigenic neuropeptides in the hypothalamus 3 h post-injection (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000302514
  • ENSP00000302274
  • ENSG00000172247
  • ENST00000642567
  • ENSP00000496508
  • ENSG00000284838

Symbol
  • CTRP4
  • CTRP4
  • ZACRP4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.73
disease
0.58
histone modification site profile
0.52
PubMedID
0.47
tissue
0.47


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.4   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 169   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.4   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 169   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0