Tbio FSD1 Fibronectin type III and SPRY domain-containing protein 1

Protein Summary

Description

May be involved in microtubule organization and stabilization. This gene encodes a centrosome associated protein that is characterized by an N-terminal coiled-coil region downstream of B-box (BBC) domain, a central fibronectin type III domain, and a C-terminal repeats in splA and RyR (SPRY) domain. The encoded protein associates with a subset of microtubules and may be involved in the stability and organization of microtubules during cytokinesis. [provided by RefSeq, Apr 2009]

Uniprot Accession IDs

• Q9BTV5
• B2RDT0
• Q9BXN0
• Q9HAG4

Gene Name

• FSD1

Ensembl ID

• ENST00000221856
• ENSP00000221856
• ENSG00000105255

Symbol

• GLFND
• MIR1
• MIR1
• GLFND

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.92
tissue sample	0.68
cellular component	0.65
gene perturbation	0.63
transcription factor	0.58

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 36.26   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 189   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 36.26   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 189   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0