Tdark RBM42 RNA-binding protein 42

Protein Summary

Description

Binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA.

Uniprot Accession IDs

• Q9BTD8
• O00320
• Q8N5R7
• Q9BU66

Gene Name

• RBM42

Ensembl ID

• ENST00000262633
• ENSP00000262633
• ENSG00000126254
• ENST00000588161
• ENSP00000466044

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.89
interacting protein	0.89
disease perturbation	0.79
gene perturbation	0.71
tissue sample	0.65

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.24   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 131   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.24   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 131   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0