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Tbio Autophagy-related protein 101

Autophagy factor required for autophagosome formation. Stabilizes ATG13, protecting it from proteasomal degradation.

 Comments

Property Summary

NCBI Gene PubMed Count 12
PubMed Score 9.13
PubTator Score 3.91

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (3)

Disease Target Count Z-score Confidence
Lung Neoplasms 232 0.0 0.0
Disease Target Count P-value
ovarian cancer 8520 2.6e-06
psoriasis 6694 9.0e-04
Disease Target Count Z-score Confidence
Smith-Magenis syndrome 29 3.735 1.9
Spinocerebellar ataxia type 7 13 3.561 1.8

Expression

  Differential Expression (2)

Disease log2 FC p
ovarian cancer 1.800 2.6e-06
psoriasis 1.200 9.0e-04

Synonym

Accession Q9BSB4 Q9HAE2 Q9HBN1
Symbols C12orf44

Gene

ATG101

  Ortholog (10)

Species Source Disease
Inparanoid OMA
Inparanoid OMA EggNOG
OMA EggNOG
OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
OMA EggNOG
OMA EggNOG
Inparanoid OMA EggNOG
OMA EggNOG

 UniProt Keyword (5)

 GO Function (2)

 GO Component (3)

 GO Process (3)

 Compartment GO Term (26)

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 GWAS Trait (3)

 HCA RNA Cell Line (56)

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Pathway (5)

Protein-protein Interaction (8)

ULK2   ULK1   RB1CC1   ATG13   CNTLN   LRRC15   FABP4   HSBP1  

PDB (2)

Gene RIF (4)

AA Sequence 

MNCRSEVLEVSVEGRQVEEAMLAVLHTVLLHRSTGKFHYKKEGTYSIGTVGTQDVDCDFIDFTYVRVSSE      1 - 70
ELDRALRKVVGEFKDALRNSGGDGLGQMSLEFYQKKKSRWPFSDECIPWEVWTVKVHVVALATEQERQIC     71 - 140
REKVGEKLCEKIINIVEVMNRHEYLPKMPTQSEVDNVFDTGLRDVQPYLYKISFQITDALGTSVTTTMRR    141 - 210
LIKDTLAL                                                                  211 - 218
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Text Mined References (17)

PMID Year Title