REEP2
Receptor expression-enhancing protein 2
Protein Summary
Required for endoplasmic reticulum (ER) network formation, shaping and remodeling. May enhance the cell surface expression of odorant receptors (By similarity). This gene encodes a member of the receptor expression enhancing protein family. Studies of a related gene in mouse suggest that the encoded protein is found in the cell membrane and enhances the function of sweet taste receptors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
- ENST00000254901
- ENSP00000254901
- ENSG00000132563
- ENST00000378339
- ENSP00000367590
- C5orf19
- SGC32445
- SPG72
- Yip2d
- C5orf19
- SGC32445
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.81 | ||
cellular component | 0.77 | ||
gene perturbation | 0.63 | ||
tissue sample | 0.58 | ||
phenotype | 0.52 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 6.23 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 330 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 6.23 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 330 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0