| Tdark | Nuclear receptor-interacting protein 2 |
Down-regulates transcriptional activation by nuclear receptors such as NR1F2.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| posterior fossa group A ependymoma | 468 | 1.3e-06 |
| atypical teratoid / rhabdoid tumor | 5112 | 3.2e-05 |
| glioblastoma | 5792 | 1.9e-04 |
| psoriasis | 6694 | 5.4e-04 |
| Pilocytic astrocytoma | 56 | 3.7e-03 |
| adult high grade glioma | 3801 | 3.9e-03 |
| colon cancer | 1478 | 7.5e-03 |
| sonic hedgehog group medulloblastoma | 467 | 1.1e-02 |
| subependymal giant cell astrocytoma | 2287 | 1.4e-02 |
| medulloblastoma, large-cell | 6241 | 4.9e-02 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -1.500 | 3.9e-03 |
| atypical teratoid / rhabdoid tumor | -1.600 | 3.2e-05 |
| colon cancer | -1.100 | 7.5e-03 |
| glioblastoma | -1.100 | 1.9e-04 |
| medulloblastoma, large-cell | -1.300 | 4.9e-02 |
| Pilocytic astrocytoma | -1.100 | 3.7e-03 |
| posterior fossa group A ependymoma | -1.300 | 1.3e-06 |
| psoriasis | -1.500 | 5.4e-04 |
| sonic hedgehog group medulloblastoma | 2.000 | 1.1e-02 |
| subependymal giant cell astrocytoma | -1.842 | 1.4e-02 |
| Species | Source | Disease |
|---|---|---|
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG |
MLFIFPLSLPWRPSCWKESCSTGQRQAGRSREDSVTPPPSSPWPTPPAGAMSTKQEARRDEGEARTRGQE 1 - 70 AQLRDRAHLSQQRRLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVIQRRLVEGNPNWLQGEPPRMQ 71 - 140 DLIHGQESRRKTSRTEIPALLVNCKCQDQLLRVAVDTGTQYNRISAGCLSRLGLEKRVLKASAGDLAPGP 141 - 210 PTQVEQLELQLGQETVVCSAQVVDAESPEFCLGLQTLLSLKCCIDLEHGVLRLKAPFSELPFLPLYQEPG 211 - 280 Q//
