Tbio AIF1L Allograft inflammatory factor 1-like

Protein Summary

Description

Actin-binding protein that promotes actin bundling. May neither bind calcium nor depend on calcium for function.

Uniprot Accession IDs

• Q9BQI0
• B2RBC4
• Q6ZR40
• Q8NAX7
• Q8WU47
• Q9H9G0

Gene Name

• AIF1L

Ensembl ID

• ENST00000247291
• ENSP00000247291
• ENSG00000126878
• ENST00000372300
• ENSP00000361374
• ENST00000372302
• ENSP00000361376
• ENST00000372309
• ENSP00000361383

Symbol

• C9orf58
• IBA2
• IBA2
• C9orf58

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.98
cellular component	0.76
PubMedID	0.69
virus perturbation	0.68
transcription factor	0.63

Protein Classes

PANTHER Classes

Protein / Calcium-binding Protein / Intracellular Calcium-sensing Protein / Calmodulin / Allograft Inflammatory Factor 1-like

Protein / Calcium-binding Protein / Annexin / Allograft Inflammatory Factor 1-like

DTO Classes

Protein / Calcium-binding Protein / Intracellular Calcium-sensing Protein / Calmodulin / Allograft Inflammatory Factor 1-like

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 27.98   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 19   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 27.98   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 19   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0