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Tbio
KXD1
KxDL motif-containing protein 1

Protein Summary
Description
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167). May be involved in the biogenesis of lysosome-related organelles such as melanosomes (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000222307
  • ENSP00000222307
  • ENSG00000105700
  • ENST00000539106
  • ENSP00000438903
  • ENST00000540691
  • ENSP00000443549
  • ENST00000595073
  • ENSP00000471554
  • ENST00000599319
  • ENSP00000468990
  • ENST00000600654
  • ENSP00000472678
  • ENST00000602094
  • ENSP00000472836

Symbol
  • C19orf50
  • KXDL
  • BORCS4
  • MST096
  • MSTP096
  • C10orf50
  • C19orf50
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
transcription factor
0.69
transcription factor perturbation
0.68
cell type or tissue
0.65
histone modification site profile
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.91   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 103   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.91   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 103   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0