Protein Summary
Plays a role in pre-mRNA alternative splicing by regulating spliceosome assembly.
- ENST00000369367
- ENSP00000358374
- ENSG00000139218
- ENST00000465950
- ENSP00000449812
- CASP11
- SFRS2IP
- SIP1
- SRSF2IP
- SIP1
- CASP11
- SFRS2IP
- SRRP129
- SRSF2IP
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.98 | ||
transcription factor perturbation | 0.98 | ||
kinase perturbation | 0.97 | ||
ligand (protein) perturbation | 0.83 | ||
histone modification site profile | 0.77 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 167.69 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 39 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 167.69 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 39 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0