Property Summary

NCBI Gene PubMed Count 9
PubMed Score 12.30
PubTator Score 5.70

Knowledge Summary


No data available


  Disease Sources (1)

Disease Target Count P-value
ependymoma 2514 3.12003686494671E-28
atypical teratoid/rhabdoid tumor 1095 1.98517299782643E-14
pilocytic astrocytoma 3086 7.41973846124702E-13
psoriasis 6685 6.52758731714311E-12
glioblastoma 5572 1.47849333774121E-8
adrenocortical carcinoma 1427 3.04933163918916E-6
adult high grade glioma 2148 2.55420089979017E-5
osteosarcoma 7933 3.15432025936592E-5
group 3 medulloblastoma 2254 5.22644498198048E-5
medulloblastoma, large-cell 6234 7.45584198570199E-5
pancreatic cancer 2300 3.80265298717433E-4
intraductal papillary-mucinous adenoma (IPMA) 2956 9.21275776799466E-4
intraductal papillary-mucinous carcinoma (IPMC) 2988 0.00407757804075759
primary pancreatic ductal adenocarcinoma 1271 0.00481459171691787
astrocytic glioma 2241 0.0100753766140844
intraductal papillary-mucinous neoplasm (IPMN) 3289 0.0157819009232036
primitive neuroectodermal tumor 3031 0.024568901253182
subependymal giant cell astrocytoma 2287 0.0347179093190177



Accession Q96S95


  Ortholog (8)

Species Source
Chimp OMA EggNOG
Macaque OMA EggNOG Inparanoid
Mouse OMA EggNOG Inparanoid
Rat OMA EggNOG Inparanoid
Cow OMA EggNOG Inparanoid
Opossum OMA EggNOG Inparanoid
Anole lizard OMA EggNOG Inparanoid
Xenopus OMA Inparanoid

Gene RIF (5)

23545117 Mutant FUS-DeltaNLS increased calcium/calmodulin-dependent protein kinase II inhibitor 2 (CAMK2N2) at both mRNA and protein levels.
23153928 Murine double minute 2 (MDM2) protein levels were decreased in AD cells relative to control lymphoblasts, suggesting an impairment of FOXO3a degradation.
20487031 We show that CaMKII N beta expression is differentially regulated by novelty and contextual fear conditioning, providing further insight into molecular basis of fear LTM.
19586909 hCaMKIINbeta may play an important role in the regulation of tumor cell growth
9724800 Functional study of the rat homolog

AA Sequence

MGEKPPSGV                                                                  71 - 79

Text Mined References (10)

PMID Year Title
23545117 2013 Genome wide array analysis indicates that an amyotrophic lateral sclerosis mutation of FUS causes an early increase of CAMK2N2 in vitro.
23153928 2013 Downregulation of extracellular signal-regulated kinase 1/2 activity by calmodulin KII modulates p21Cip1 levels and survival of immortalized lymphocytes from Alzheimer's disease patients.
22472876 2013 A mega-analysis of genome-wide association studies for major depressive disorder.
20487031 2010 Differential regulation of CaMKII inhibitor beta protein expression after exposure to a novel context and during contextual fear memory formation.
19586909 2009 Endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest and apoptosis through down-regulation of the phosphatidylinositide 3-kinase/Akt/HDM2 pathway.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12531901 2003 RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11444830 2001 Molecular cloning and characterization of a novel calcium/calmodulin-dependent protein kinase II inhibitor from human dendritic cells.
9724800 1998 Characterization of a calmodulin kinase II inhibitor protein in brain.