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Tbio
VPS13A
Vacuolar protein sorting-associated protein 13A

Protein Summary
Description
May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane. The protein encoded by this gene may control steps in the cycling of proteins through the trans-Golgi network to endosomes, lysosomes and the plasma membrane. Mutations in this gene cause the autosomal recessive disorder, chorea-acanthocytosis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000357409
  • ENSP00000349985
  • ENSG00000197969
  • ENST00000360280
  • ENSP00000353422
  • ENST00000376634
  • ENSP00000365821
  • ENST00000376636
  • ENSP00000365823
  • ENST00000643348
  • ENSP00000493592
  • ENST00000644843
  • ENSP00000494809
  • ENST00000645632
  • ENSP00000496361

Symbol
  • CHAC
  • KIAA0986
  • CHAC
  • CHOREIN
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.91
kinase perturbation
0.84
virus perturbation
0.79
transcription factor binding site profile
0.7
cell line
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 252.63   (req: < 5)
Gene RIFs: 37   (req: <= 3)
Antibodies: 31   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 252.63   (req: >= 5)
Gene RIFs: 37   (req: > 3)
Antibodies: 31   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0