| Tbio | Protein C8orf37 |
This gene encodes a ubiquitously expressed protein of unknown function. It has high levels of mRNA expression in the brain, heart, and retina and the protein co-localizes with polyglutamylated tubulin at the base of the primary cilium in human retinal pigment epithelial cells. Mutations in this gene have been associated with autosomal recessive cone-rod dystrophy (arCRD) and retinitis pigmentosa (arRP). [provided by RefSeq, Mar 2012]
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Retinitis Pigmentosa | 226 | 4.232 | 2.1 |
| BARDET-BIEDL SYNDROME 21 | 1 | 0.0 | 0.0 |
| CONE-ROD DYSTROPHY 16 | 1 | 0.0 | 0.0 |
| Disease | Target Count | P-value |
|---|---|---|
| ependymoma | 4679 | 1.2e-14 |
| lung carcinoma | 2843 | 9.6e-11 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Bardet-Biedl syndrome | 51 | 3.392 | 1.7 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Hematocele of tunica vaginalis testis | 3 | 4.975 | 2.5 |
| Polydactyly | 107 | 4.17 | 2.1 |
| Fundus dystrophy | 83 | 4.101 | 2.1 |
| Disease | Target Count |
|---|---|
| cone-rod dystrophy | 59 |
