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Tdark UBX domain-containing protein 10

VCP/p97-binding protein required for ciliogenesis (PubMed:26389662). Acts as a tethering factor that facilitates recruitment of VCP/p97 to the intraflagellar transport complex B (IFT-B) in cilia (PubMed:26389662). UBX domain-containing proteins act as tethering factors for VCP/p97 and may specify substrate specificity of VCP/p97 (PubMed:26389662).

 Comments

Property Summary

NCBI Gene PubMed Count 5
PubMed Score 1.04
PubTator Score 0.89

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 0.5

Expression

  Differential Expression (11)

Disease log2 FC p
chronic rhinosinusitis -1.474 1.6e-02
cystic fibrosis and chronic rhinosinusit... -1.331 3.2e-02
ductal carcinoma in situ 1.200 1.3e-02
ependymoma 1.100 3.0e-04
group 3 medulloblastoma -1.200 1.2e-03
intraductal papillary-mucinous adenoma (... 2.900 3.8e-04
intraductal papillary-mucinous carcinoma... 2.800 3.8e-04
intraductal papillary-mucinous neoplasm ... 3.000 2.2e-03
nasopharyngeal carcinoma -1.900 7.2e-08
osteosarcoma -1.023 1.4e-04
psoriasis -1.300 4.1e-61

Synonym

Accession Q96LJ8 Q5R386
Symbols UBXD3

Gene

UBXN10

  Ortholog (10)

Species Source Disease
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
OMA EggNOG

 UniProt Keyword (6)

 GO Component (1)

 GO Process (1)

 Compartment GO Term (8)

 HCA RNA Cell Line (38)

See all...

Gene RIF (1)

AA Sequence 

MATEAPVNIAPPECSTVVSTAVDSLIWQPNSLNMHMIRPKSAKGRTRPSLQKSQGVEVCAHHIPSPPPAI      1 - 70
PYELPSSQKPGACAPKSPNQGASDEIPELQQQVPTGASSSLNKYPVLPSINRKNLEEEAVETVAKKASSL     71 - 140
QLSSIRALYQDETGTMKTSEEDSRARACAVERKFIVRTKKQGSSRAGNLEEPSDQEPRLLLAVRSPTGQR    141 - 210
FVRHFRPTDDLQTIVAVAEQKNKTSYRHCSIETMEVPRRRFSDLTKSLQECRIPHKSVLGISLEDGEGWP    211 - 280
//

Text Mined References (7)

PMID Year Title