| Tdark | UBX domain-containing protein 10 |
VCP/p97-binding protein required for ciliogenesis (PubMed:26389662). Acts as a tethering factor that facilitates recruitment of VCP/p97 to the intraflagellar transport complex B (IFT-B) in cilia (PubMed:26389662). UBX domain-containing proteins act as tethering factors for VCP/p97 and may specify substrate specificity of VCP/p97 (PubMed:26389662).
Comments
| Disease | Target Count | P-value |
|---|---|---|
| psoriasis | 6694 | 4.1e-61 |
| nasopharyngeal carcinoma | 1058 | 7.2e-08 |
| osteosarcoma | 7950 | 1.4e-04 |
| ependymoma | 4679 | 3.0e-04 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 3.8e-04 |
| intraductal papillary-mucinous adenoma (IPMA) | 2955 | 3.8e-04 |
| group 3 medulloblastoma | 4104 | 1.2e-03 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 2.2e-03 |
| ductal carcinoma in situ | 1745 | 1.3e-02 |
| chronic rhinosinusitis | 512 | 1.6e-02 |
| cystic fibrosis and chronic rhinosinusitis | 214 | 3.2e-02 |
| Disease | log2 FC | p |
|---|---|---|
| chronic rhinosinusitis | -1.474 | 1.6e-02 |
| cystic fibrosis and chronic rhinosinusit... | -1.331 | 3.2e-02 |
| ductal carcinoma in situ | 1.200 | 1.3e-02 |
| ependymoma | 1.100 | 3.0e-04 |
| group 3 medulloblastoma | -1.200 | 1.2e-03 |
| intraductal papillary-mucinous adenoma (... | 2.900 | 3.8e-04 |
| intraductal papillary-mucinous carcinoma... | 2.800 | 3.8e-04 |
| intraductal papillary-mucinous neoplasm ... | 3.000 | 2.2e-03 |
| nasopharyngeal carcinoma | -1.900 | 7.2e-08 |
| osteosarcoma | -1.023 | 1.4e-04 |
| psoriasis | -1.300 | 4.1e-61 |
MATEAPVNIAPPECSTVVSTAVDSLIWQPNSLNMHMIRPKSAKGRTRPSLQKSQGVEVCAHHIPSPPPAI 1 - 70 PYELPSSQKPGACAPKSPNQGASDEIPELQQQVPTGASSSLNKYPVLPSINRKNLEEEAVETVAKKASSL 71 - 140 QLSSIRALYQDETGTMKTSEEDSRARACAVERKFIVRTKKQGSSRAGNLEEPSDQEPRLLLAVRSPTGQR 141 - 210 FVRHFRPTDDLQTIVAVAEQKNKTSYRHCSIETMEVPRRRFSDLTKSLQECRIPHKSVLGISLEDGEGWP 211 - 280 //
