RHOV
Rho-related GTP-binding protein RhoV
Protein Summary
Plays a role in the control of the actin cytoskeleton via activation of the JNK pathway.
- ENST00000220507
- ENSP00000220507
- ENSG00000104140
- ARHV
- WRCH2
- CHP
- ARHV
- WRCH2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
molecular function | 0.81 | ||
histone modification site profile | 0.72 | ||
cell type or tissue | 0.7 | ||
gene perturbation | 0.63 | ||
transcription factor | 0.62 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 41.74 (req: < 5)
Gene RIFs: 11 (req: <= 3)
Antibodies: 16 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 41.74 (req: >= 5)
Gene RIFs: 11 (req: > 3)
Antibodies: 16 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 13
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0