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Tbio
MS4A4A
Membrane-spanning 4-domains subfamily A member 4A

Protein Summary
Description
May be involved in signal transduction as a component of a multimeric receptor complex. This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features, similar intron/exon splice boundaries, and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000337908
  • ENSP00000338648
  • ENSG00000110079
  • ENST00000532114
  • ENSP00000434506

Symbol
  • 4SPAN1
  • CD20L1
  • MS4A4
  • MS4A4
  • MS4A7
  • 4SPAN1
  • CD20L1
  • CD20-L1
  • HDCME31P
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.63
tissue sample
0.61
cell line
0.5
phenotype
0.44
microRNA
0.42


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.61   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 156   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.61   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 156   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0