Tdark TPD52L3 Tumor protein D55

Protein Summary

Description

This gene encodes a member of the tumor protein D52-like family of proteins. These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins. The encoded protein may play a role in spermatogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Uniprot Accession IDs

• Q96J77
• Q5TCR3
• Q5TCR4
• Q5TCR5
• Q8N4P5
• Q8WWF7
• Q96M09
• hD55

Gene Name

• TPD52L3

Ensembl ID

• ENST00000314556
• ENSP00000318665
• ENSG00000170777
• ENST00000344545
• ENSP00000341677
• ENST00000381428
• ENSP00000370836

Symbol

• D55
• hD55
• NYDSP25

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.75
gene perturbation	0.65
cell line	0.54
microRNA	0.54
tissue	0.54

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.6   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 239   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.6   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 239   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0