Tbio PEX11G Peroxisomal membrane protein 11C

Protein Summary

Description

Promotes membrane protrusion and elongation on the peroxisomal surface. The protein encoded by this gene is a member of the PEX11 family. This family is reported to regulate the number and size of peroxisomes in evolutionarily distant organisms. The protein encoded by this gene may induce clustering of peroxisomes. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

Uniprot Accession IDs

• Q96HA9
• Q8NDM0

Gene Name

• PEX11G

Ensembl ID

• ENST00000221480
• ENSP00000221480
• ENSG00000104883
• ENST00000593942
• ENSP00000472216

Symbol

• PEX11C

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.88
cell type or tissue	0.84
cellular component	0.64
tissue sample	0.62
cell line	0.48

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.73   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 59   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.73   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 59   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0