Tdark | BLOC-1-related complex subunit 8 |
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.
Comments
Disease | Target Count | P-value |
---|---|---|
posterior fossa group B ependymoma | 1530 | 1.86760948070651E-9 |
atypical teratoid / rhabdoid tumor | 4369 | 3.10231938728086E-9 |
osteosarcoma | 7933 | 8.55526015605324E-8 |
pilocytic astrocytoma | 3086 | 1.65525355016753E-6 |
glioblastoma | 5572 | 2.14955135153292E-5 |
ovarian cancer | 8492 | 4.08829313089702E-5 |
malignant mesothelioma | 3163 | 5.92604220847479E-5 |
adult high grade glioma | 2148 | 7.88525331995241E-5 |
subependymal giant cell astrocytoma | 2287 | 0.00286085946069272 |
astrocytic glioma | 2241 | 0.00820806637870597 |
Disease | log2 FC | p |
---|---|---|
malignant mesothelioma | -1.200 | 0.000 |
astrocytic glioma | -1.100 | 0.008 |
osteosarcoma | -3.018 | 0.000 |
posterior fossa group B ependymoma | 1.700 | 0.000 |
glioblastoma | -1.500 | 0.000 |
atypical teratoid / rhabdoid tumor | -1.600 | 0.000 |
adult high grade glioma | -1.500 | 0.000 |
pilocytic astrocytoma | -1.400 | 0.000 |
subependymal giant cell astrocytoma | 1.733 | 0.003 |
ovarian cancer | 1.600 | 0.000 |
Species | Source |
---|---|
Zebrafish | EggNOG Inparanoid |
C. elegans | EggNOG Inparanoid |
Fruitfly | EggNOG Inparanoid |
PMID | Text |
---|---|
20628086 | Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
20379614 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) |
19913121 | Observational study of gene-disease association. (HuGE Navigator) |
PMID | Year | Title |
---|---|---|
27107012 | 2016 | Pooled-matrix protein interaction screens using Barcode Fusion Genetics. |
25898167 | 2015 | BORC, a multisubunit complex that regulates lysosome positioning. |
25416956 | 2014 | A proteome-scale map of the human interactome network. |
23186163 | 2013 | Toward a comprehensive characterization of a human cancer cell phosphoproteome. |
20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. |
20379614 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | |
19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. |
16344560 | 2006 | Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |
16189514 | 2005 | Towards a proteome-scale map of the human protein-protein interaction network. |
15489334 | 2004 | The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
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