Property Summary

NCBI Gene PubMed Count 9
PubMed Score 4.59
PubTator Score 1.77

Knowledge Summary


No data available


  Disease Sources (4)

Disease Target Count P-value
ovarian cancer 8492 6.28949983058035E-5
posterior fossa group B ependymoma 1530 1.26400221421451E-4
pancreatic cancer 2300 0.0105490793577591
pancreatic carcinoma 567 0.0105490793577591
group 3 medulloblastoma 2254 0.0178409128794935
acute myeloid leukemia 785 0.0337555116712651
Disease Target Count Z-score Confidence
Congenital myasthenic syndrome 28 4.68 2.3
Disease Target Count
Myasthenic syndrome, congenital, 15 1


  Differential Expression (6)

Disease log2 FC p
pancreatic cancer 1.400 0.011
group 3 medulloblastoma 1.100 0.018
posterior fossa group B ependymoma 1.300 0.000
pancreatic carcinoma 1.400 0.011
acute myeloid leukemia -1.600 0.034
ovarian cancer 1.700 0.000


Accession Q96F25 A8K030
Symbols CMS15


  Ortholog (10)

Species Source
Chimp OMA EggNOG
Mouse OMA EggNOG Inparanoid
Rat OMA EggNOG Inparanoid
Dog OMA EggNOG Inparanoid
Cow OMA EggNOG Inparanoid
Opossum OMA EggNOG Inparanoid
Chicken OMA EggNOG
Anole lizard OMA EggNOG Inparanoid
Fruitfly EggNOG Inparanoid
S.cerevisiae OMA EggNOG Inparanoid

Gene RIF (3)

23404334 We identify ALG14 and ALG2 as novel genes in which mutations cause a congenital myasthenic syndrome
18976975 Knockdown of asparagine-linked glycosylation 14 homolog (ALG14) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells
16100110 ALG13 and ALG14 form a functional endoplasmic reticulum UDP-N-acetylglucosamine transferase

AA Sequence

YLGRIV                                                                    211 - 216

Text Mined References (9)

PMID Year Title
23404334 2013 Congenital myasthenic syndromes due to mutations in ALG2 and ALG14.
23362303 2013 Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.
22359512 2012 Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.
17686769 2007 Membrane topology of the Alg14 endoplasmic reticulum UDP-GlcNAc transferase subunit.
16100110 2005 Alg14 recruits Alg13 to the cytoplasmic face of the endoplasmic reticulum to form a novel bipartite UDP-N-acetylglucosamine transferase required for the second step of N-linked glycosylation.
15615718 2005 Two proteins homologous to the N- and C-terminal domains of the bacterial glycosyltransferase Murg are required for the second step of dolichyl-linked oligosaccharide synthesis in Saccharomyces cerevisiae.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.