Property Summary

NCBI Gene PubMed Count 12
PubMed Score 1.08
PubTator Score 2.07

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (2)

Disease Target Count P-value
malignant mesothelioma 3163 1.14787493674274E-6
ovarian cancer 8492 1.61573030803345E-6
Multiple myeloma 1328 9.4532218870609E-4
Pneumonia 133 0.00982247392436824
intraductal papillary-mucinous carcinoma (IPMC) 2988 0.0168891401366011
Disease Target Count Z-score Confidence
Acrocallosal syndrome 12 4.283 2.1

Expression

  Differential Expression (5)

Disease log2 FC p
Multiple myeloma 1.779 0.001
malignant mesothelioma -1.300 0.000
intraductal papillary-mucinous carcinoma... -1.300 0.017
Pneumonia -1.100 0.010
ovarian cancer -2.100 0.000

Synonym

Accession Q96EI5 Q8WY12 Q9H2H1 Q9H775 TCEA-like protein 4
Symbols WEX7
NPD017

Gene

PANTHER Protein Class (1)

Gene RIF (1)

PMID Text
17076909 Expression of TCEAL4 was down-regulated in all anaplastic thyroid carcinomas studied. Loss of TCEAL4 expression might be associated with development of ATC from pre-existing diffferentiated TC.

AA Sequence

MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGE      1 - 70
AKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKE     71 - 140
YKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFLWMQRNLQDPFYPRGPREFRGGCRAPRRDIE    141 - 210
DIPYV                                                                     211 - 215
//

Text Mined References (18)

PMID Year Title
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
22814378 2012 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
21269460 2011 Initial characterization of the human central proteome.
19413330 2009 Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
18669648 2008 A quantitative atlas of mitotic phosphorylation.
17207965 2007 hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
17081983 2006 Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
17076909 2006 Down-regulation of transcription elogation factor A (SII) like 4 (TCEAL4) in anaplastic thyroid cancer.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
More...