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Tbio
CMTM5
CKLF-like MARVEL transmembrane domain-containing protein 5

Protein Summary
Description
This gene encodes a member of the chemokine-like factor superfamily. This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules. The encoded protein may exhibit tumor suppressor activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000339180
  • ENSP00000344819
  • ENSG00000166091
  • ENST00000342473
  • ENSP00000344160
  • ENST00000359320
  • ENSP00000352270
  • ENST00000382809
  • ENSP00000372259
  • ENST00000397227
  • ENSP00000380404
  • ENST00000649278
  • ENSP00000497215

Symbol
  • CKLFSF5
  • CKLFSF5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.59
kinase perturbation
0.48
tissue
0.46
transcription factor
0.46
biological term
0.4


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.2   (req: < 5)
Gene RIFs: 18   (req: <= 3)
Antibodies: 214   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.2   (req: >= 5)
Gene RIFs: 18   (req: > 3)
Antibodies: 214   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0