| Tdark | Mas-related G-protein coupled receptor member F |
Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity).
Comments
| Disease | log2 FC | p |
|---|---|---|
| cystic fibrosis | -1.304 | 0.000 |
| primary pancreatic ductal adenocarcinoma | 1.186 | 0.003 |
| intraductal papillary-mucinous adenoma (... | -2.300 | 0.000 |
| intraductal papillary-mucinous carcinoma... | -2.200 | 0.000 |
| intraductal papillary-mucinous neoplasm ... | -2.200 | 0.002 |
| breast carcinoma | -1.400 | 0.000 |
| Breast cancer | -1.400 | 0.000 |
| ductal carcinoma in situ | -1.500 | 0.007 |
| invasive ductal carcinoma | -2.700 | 0.000 |
| ovarian cancer | -3.400 | 0.000 |
| head and neck cancer | -1.300 | 0.029 |
| Accession | Q96AM1 B3KV43 Q8NBK8 Mas-related gene F protein |
| Symbols |
RTA MRGF GPR140 GPR168 |
| Bryan Roth | functional assay |
| Steve Finkbeiner | Neuron specific phenotypes being screened |
MAGNCSWEAHPGNRNKMCPGLSEAPELYSRGFLTIEQIAMLPPPAVMNYIFLLLCLCGLVGNGLVLWFFG 1 - 70 FSIKRNPFSIYFLHLASADVGYLFSKAVFSILNTGGFLGTFADYIRSVCRVLGLCMFLTGVSLLPAVSAE 71 - 140 RCASVIFPAWYWRRRPKRLSAVVCALLWVLSLLVTCLHNYFCVFLGRGAPGAACRHMDIFLGILLFLLCC 141 - 210 PLMVLPCLALILHVECRARRRQRSAKLNHVILAMVSVFLVSSIYLGIDWFLFWVFQIPAPFPEYVTDLCI 211 - 280 CINSSAKPIVYFLAGRDKSQRLWEPLRVVFQRALRDGAELGEAGGSTPNTVTMEMQCPPGNAS 281 - 343 //
| PMID | Year | Title |
|---|---|---|
| 24583173 | 2014 | Comparative genomic analysis of eutherian Mas-related G protein-coupled receptor genes. |
| 23376485 | 2013 | Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. |
| 16303743 | 2005 | Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |
| 15489334 | 2004 | The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
| 15342556 | 2004 | Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |
| 14702039 | 2004 | Complete sequencing and characterization of 21,243 full-length human cDNAs. |
| 12477932 | 2002 | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |
| 11551509 | 2001 | A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. |
| 11181995 | 2001 | The sequence of the human genome. |
| 2109324 | 1990 | RTA, a candidate G protein-coupled receptor: cloning, sequencing, and tissue distribution. |
