| Tdark | Mas-related G-protein coupled receptor member F |
Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity).
Comments
| Disease | Target Count | P-value |
|---|---|---|
| Breast cancer | 3578 | 6.5e-19 |
| ovarian cancer | 8520 | 2.5e-16 |
| cystic fibrosis | 1696 | 1.4e-05 |
| intraductal papillary-mucinous adenoma (IPMA) | 2955 | 3.4e-05 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 6.2e-05 |
| invasive ductal carcinoma | 2951 | 1.2e-04 |
| breast carcinoma | 1638 | 2.9e-04 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 2.1e-03 |
| primary pancreatic ductal adenocarcinoma | 1109 | 3.2e-03 |
| ductal carcinoma in situ | 1745 | 6.8e-03 |
| head and neck cancer | 271 | 2.9e-02 |
| Disease | log2 FC | p |
|---|---|---|
| Breast cancer | -1.400 | 6.5e-19 |
| breast carcinoma | -1.400 | 2.9e-04 |
| cystic fibrosis | -1.304 | 1.4e-05 |
| ductal carcinoma in situ | -1.500 | 6.8e-03 |
| head and neck cancer | -1.300 | 2.9e-02 |
| intraductal papillary-mucinous adenoma (... | -2.300 | 3.4e-05 |
| intraductal papillary-mucinous carcinoma... | -2.200 | 6.2e-05 |
| intraductal papillary-mucinous neoplasm ... | -2.200 | 2.1e-03 |
| invasive ductal carcinoma | -2.700 | 1.2e-04 |
| ovarian cancer | -3.400 | 2.5e-16 |
| primary pancreatic ductal adenocarcinoma | 1.186 | 3.2e-03 |
MAGNCSWEAHPGNRNKMCPGLSEAPELYSRGFLTIEQIAMLPPPAVMNYIFLLLCLCGLVGNGLVLWFFG 1 - 70 FSIKRNPFSIYFLHLASADVGYLFSKAVFSILNTGGFLGTFADYIRSVCRVLGLCMFLTGVSLLPAVSAE 71 - 140 RCASVIFPAWYWRRRPKRLSAVVCALLWVLSLLVTCLHNYFCVFLGRGAPGAACRHMDIFLGILLFLLCC 141 - 210 PLMVLPCLALILHVECRARRRQRSAKLNHVILAMVSVFLVSSIYLGIDWFLFWVFQIPAPFPEYVTDLCI 211 - 280 CINSSAKPIVYFLAGRDKSQRLWEPLRVVFQRALRDGAELGEAGGSTPNTVTMEMQCPPGNAS 281 - 343 //
