Tbio CPNE4 Copine-4

Protein Summary

Description

Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes. This gene belongs to the highly conserved copine family. It encodes a calcium-dependent, phospholipid-binding protein, which may be involved in membrane trafficking, mitogenesis and development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Uniprot Accession IDs

• Q96A23
• D3DNC5
• Q8TEX1

Gene Name

• CPNE4

Ensembl ID

• ENST00000429747
• ENSP00000411904
• ENSG00000196353
• ENST00000502818
• ENSP00000421646
• ENST00000511604
• ENSP00000423811
• ENST00000512055
• ENSP00000421705
• ENST00000512332
• ENSP00000424853
• ENST00000617767
• ENSP00000478878

Symbol

• CPN4
• COPN4

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
trait	1
cell type or tissue	0.76
transcription factor binding site profile	0.61
virus perturbation	0.59
disease	0.57

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.93   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 77   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.93   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 77   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0