Property Summary

NCBI Gene PubMed Count 9
Grant Count 4
R01 Count 4
Funding $277,720.5
PubMed Score 1.15
PubTator Score 2.64

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (10)

Disease log2 FC p
osteosarcoma -1.765 0.002
adrenocortical carcinoma -1.232 0.000
breast carcinoma -1.300 0.000
fibroadenoma -1.200 0.028
group 3 medulloblastoma -2.000 0.001
subependymal giant cell astrocytoma 1.579 0.013
spina bifida -1.116 0.042
ductal carcinoma in situ -1.200 0.008
invasive ductal carcinoma -2.100 0.000
ovarian cancer -1.400 0.000

Synonym

Accession Q969T3 Q5JZH5 Q5JZH6 Q5JZH7 Q8WUR6 Q9BR16
Symbols SNX-L
PP3993
C20orf161
dJ337O18.4

Gene

Gene RIF (1)

PMID Text
12459172 Data suggest that human sorting nexin-L (SNX-L) may be a regulatory gene involved in receptor protein degradation during embryonic liver development.

AA Sequence

MHRGTQEGAMASRLLHRLRHALAGDGPGEAAASPEAEQFPESSELEDDDAEGLSSRLSGTLSFTSAEDDE      1 - 70
DDEDEDDEEAGPDQLPLGDGTSGEDAERSPPPDGQWGSQLLARQLQDFWKKSRNTLAPQRLLFEVTSANV     71 - 140
VKDPPSKYVLYTLAVIGPGPPDCQPAQISRRYSDFERLHRNLQRQFRGPMAAISFPRKRLRRNFTAETIA    141 - 210
RRSRAFEQFLGHLQAVPELRHAPDLQDFFVLPELRRAQSLTCTGLYREALALWANAWQLQAQLGTPSGPD    211 - 280
RPLLTLAGLAVCHQELEDPGEARACCEKALQLLGDKSLHPLLAPFLEAHVRLSWRLGLDKRQSEARLQAL    281 - 350
QEAGLTPTPPPSLKELLIKEVLD                                                   351 - 373
//

Text Mined References (10)

PMID Year Title
26871637 2016 Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12461558 2002 Sorting out the cellular functions of sorting nexins.
12459172 2002 Expression of a novel member of sorting nexin gene family, SNX-L, in human liver development.
11780052 2001 The DNA sequence and comparative analysis of human chromosome 20.
11736640 2001 The Phox homology (PX) domain, a new player in phosphoinositide signalling.
11485546 2001 A large family of endosome-localized proteins related to sorting nexin 1.