Tbio ARL11 ADP-ribosylation factor-like protein 11

Protein Summary

Description

May play a role in apoptosis. May act as a tumor suppressor. This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers. [provided by RefSeq, May 2010]

Uniprot Accession IDs

• Q969Q4

Gene Name

• ARL11

Ensembl ID

• ENST00000282026
• ENSP00000282026
• ENSG00000152213

Symbol

• ARLTS1
• ARLTS1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.76
tissue sample	0.61
virus perturbation	0.59
protein domain	0.58
microRNA	0.53

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.02   (req: < 5)

Gene RIFs: 17   (req: <= 3)

Antibodies: 181   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.02   (req: >= 5)

Gene RIFs: 17   (req: > 3)

Antibodies: 181   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0