Tdark DDX12P Putative ATP-dependent RNA helicase DDX12

Protein Summary

Description

DNA helicase involved in cellular proliferation. Probably required for maintaining the chromosome segregation (By similarity).

Uniprot Accession IDs

• Q92771

Gene Name

• DDX12P

Symbol

• CHLR2
• DDX12
• CHLR2
• DDX12

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell line	0.73
histone modification site profile	0.72
tissue sample	0.65
transcription factor	0.56
cellular component	0.48

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Helicase / Dna Helicase / Putative Atp-dependent Rna Helicase Ddx12

Protein / Nucleic Acid Binding / Dna Binding Protein / Dna Helicase / Putative Atp-dependent Rna Helicase Ddx12

DTO Classes

Protein / Enzyme / Helicase / Dna Helicase / Putative Atp-dependent Rna Helicase Ddx12

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 0   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0