Tdark TMEM131 Transmembrane protein 131

Protein Summary

Description

May play a role in the immune response to viral infection.

Uniprot Accession IDs

• Q92545

Gene Name

• TMEM131

Ensembl ID

• ENST00000186436
• ENSP00000186436
• ENSG00000075568

Symbol

• KIAA0257
• RW1
• RW1
• CC28
• YR-23
• PRO1048

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	0.96
transcription factor binding site profile	0.91
tissue sample	0.66
histone modification site profile	0.64
kinase perturbation	0.6

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 75.02   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 20   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 75.02   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 20   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0