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Tbio
RSPH1
Radial spoke head 1 homolog

Protein Summary
Description
May play an important role in male meiosis (By similarity). It is necessary for proper building of the axonemal central pair and radial spokes. This gene encodes a male meiotic metaphase chromosome-associated acidic protein. This gene is expressed in tissues with motile cilia or flagella, including the trachea, lungs, airway brushings, and testes. Mutations in this gene result in primary ciliary dyskinesia-24. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000291536
  • ENSP00000291536
  • ENSG00000160188
  • ENST00000398352
  • ENSP00000381395

Symbol
  • TSA2
  • TSGA2
  • CT79
  • TSA2
  • RSP44
  • TSGA2
  • RSPH10A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.84
transcription factor
0.6
cell type or tissue
0.58
transcription factor binding site profile
0.58
tissue sample
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 47.02   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 61   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 47.02   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0