Tbio CNTNAP5 Contactin-associated protein-like 5

Protein Summary

Description

May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication. This gene product belongs to the neurexin family, members of which function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q8WYK1
• Q4ZFW2
• Q4ZG21
• Q53R09
• Q53RX1
• Q53SG3
• Q584P3
• Q96MS7

Gene Name

• CNTNAP5

Ensembl ID

• ENST00000431078
• ENSP00000399013
• ENSG00000155052

Symbol

• CASPR5
• caspr5

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
trait	1
protein domain	0.92
phenotype	0.79
cell line	0.64
disease	0.59

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.14   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 20   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.14   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 20   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0