DNAH7
Dynein heavy chain 7, axonemal
Protein Summary
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity). DNAH7 is a component of the inner dynein arm of ciliary axonemes (Zhang et al., 2002 [PubMed 11877439]).[supplied by OMIM, Mar 2008]
- ENST00000312428
- ENSP00000311273
- ENSG00000118997
- ENST00000409063
- ENSP00000386912
- ENST00000410072
- ENSP00000386260
- KIAA0944
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 1 | ||
molecular function | 0.96 | ||
cell type or tissue | 0.81 | ||
histone modification site profile | 0.76 | ||
cellular component | 0.69 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 11.02 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 35 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 11.02 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 35 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 11
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0