Tdark XAGE5 X antigen family member 5

Protein Summary

Description

This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q8WWM1
• Q5JS81
• XAGE-5

Gene Name

• XAGE5

Ensembl ID

• ENST00000351072
• ENSP00000342240
• ENSG00000171405
• ENST00000375501
• ENSP00000364651

Symbol

• GAGED5
• CT12.5
• GAGED5
• XAGE-5

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.99
cellular component	0.64
cell line	0.45
tissue sample	0.34
virus perturbation	0.21

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.21   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 4   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.21   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 4   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0