Property Summary

NCBI Gene PubMed Count 14
PubMed Score 6.33
PubTator Score 3.83

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (9)

Disease log2 FC p
Multiple myeloma 2.017 0.000
psoriasis 1.100 0.000
osteosarcoma 2.436 0.000
Amyotrophic Lateral Sclerosis 1.022 0.000
acute quadriplegic myopathy 1.249 0.000
Parkinson's disease -1.200 0.038
lung adenocarcinoma 1.157 0.000
ovarian cancer 2.900 0.000
dermatomyositis 1.100 0.003

Synonym

Accession Q8WU90 B4DMW2 D3DPG7 Q5QTQ4 Q8WZ06 Q9NUZ3 Q9NZ37 Q9P079
Symbols HT010
LEREPO4
MSTP012

Gene

Gene RIF (3)

PMID Text
23711155 Lerepo4 action leaves Drg1 affinity for nucleotides unaffected, feasibly favoring a switch I reorientation, mainly via the TGS domain.
23624947 it is hypothesized that ZC3H15 may interact with TRAF-2 functionally within the NF-kappaB pathway, and may be explored as a potential target in acute myeloid leukemia
20925576 down-regulation of LEREPO4 expression caused a significant inhibition of HIV replication

AA Sequence

MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLK      1 - 70
KDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDA     71 - 140
RDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHA    141 - 210
LPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKAD    211 - 280
FKAGKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLYIPRDVDETGITVA    281 - 350
SLERFSTYTSDKDENKLSEASGGRAENGERSDLEEDNEREGTENGAIDAVPVDENLFTGEDLDELEEELN    351 - 420
TLDLEE                                                                    421 - 426
//

Text Mined References (27)

PMID Year Title
25944712 2015 N-terminome analysis of the human mitochondrial proteome.
25468996 2014 E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
25416956 2014 A proteome-scale map of the human interactome network.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
23711155 2013 Human Drg1 is a potassium-dependent GTPase enhanced by Lerepo4.
23624947 2013 Characterization of ZC3H15 as a potential TRAF-2-interacting protein implicated in the NF?B pathway and overexpressed in AML.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
22681889 2012 The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
22658674 2012 Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
21516116 2011 Next-generation sequencing to generate interactome datasets.
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